Each capsule contains white or almost white spherical microgranules. The recommended dose is 30 mg once daily for 2 weeks. In patients not fully healed within this time, the medication is continued at the same dose for another two weeks. Treatment of gastric ulcer: The recommended dose is 30 mg once daily for 4 weeks. The ulcer usually heals within 4 weeks, but in patients not fully healed within this time, the medication may be continued at the same dose for another 4 weeks.
In patients not fully healed within this time, the treatment may be continued at the same dose for another 4 weeks. Prophylaxis of reflux oesophagitis: The dose may be increased up to 30 mg daily as necessary. Eradication of Helicobacter pylori: When selecting appropriate combination therapy consideration should be given to official local guidance regarding bacterial resistance, duration of treatment, most commonly 7 days but sometimes up to 14 days , and appropriate use of antibacterial agents.
The recommended dose is 30 mg of lansoprazole twice daily for 7 days in combination with one of the following: Six months after successful eradication treatment, the risk of re-infection is low and relapse is therefore unlikely. Use of a regimen including lansoprazole 30 mg twice daily, amoxicillin 1 g twice daily and metronidazole mg twice daily has also been examined. Lower eradication rates were seen using this combination than in regimens involving clarithromycin. It may be suitable for those who are unable to take clarithromycin as part of an eradication therapy, when local resistance rates to metronidazole are low.
In patients not fully healed the treatment may be continued for another four weeks. If the treatment fails the dose 30 mg once daily should be used. Symptomatic gastro-oesophageal reflux disease: The recommended dose is 15 mg or 30 mg daily. It may harm them, even if their signs of illness are the same as yours. What is in this leaflet 1. Possible side effects 5.
Contents of the pack and other information OWhat Lansoprazole Gastro-resistant Capsules are and what they are used for Lansoprazole belongs to a group of medicines called proton pump inhibitors. You have been given lansoprazole because you have a condition caused by stomach acid.
Your doctor may prescribe Lansoprazole for: Warning and precautions Talk to your doctor or pharmacist before taking Lansoprazole Gastro-resistant Capsules: Your doctor will decide if you should take Lansoprazole Gastro-resistant Capsules. If lesions occur, especially in sun-exposed areas of the skin, and if accompanied by arthralgia, the patient should seek medical help promptly and the health care professional should consider stopping lansoprazole.
SCLE after previous treatment with a proton pump inhibitor may increase the risk of SCLE with other proton pump inhibitors see section 4. This medicine contains sucrose. Patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase insufficiency should not take this medicine.
Lansoprazole may interfere with the absorption of drugs where gastric pH is critical to bioavailability. The absorption of ketoconazole and itraconazole from the gastrointestinal tract is enhanced by the presence of gastric acid. Administration of lansoprazole may result in sub-therapeutic concentrations of ketoconazole and itraconazole and the combination should be avoided. Co-administration of lansoprazole and digoxin may lead to increased digoxin plasma levels.
The plasma levels of digoxin should therefore be monitored and the dose of digoxin adjusted if necessary when initiating and ending lansoprazole treatment. Medicinal products metabolised by P enzymes Lansoprazole may increase plasma concentrations of drugs that are metabolised by CYP3A4. Caution is advised when combining lansoprazole with drugs which are metabolised by this enzyme and have a narrow therapeutic window.
Increases in INR and prothrombin time may lead to abnormal bleeding and even death. Patients treated with lansoprazole and warfarin concomitantly may need to be monitored for increase in INR and prothrombin time. Lansoprazole reduces the plasma concentration of theophylline, which may decrease the expected clinical effect at the dose. Patient monitoring should be taken in co-administration of lansoprazole with theophylline. Co-administration of lansoprazole increases the plasma concentrations of tacrolimus a CYP3A and P-gp substrate.
Monitoring of tacrolimus plasma concentrations is advised when concomitant treatment with lanzoprazole is initiated or ended. Medicinal products transported by P-glycoprotein Lansoprazole has been observed to inhibit the transport protein, P-glycoprotein P-gp in vitro.
The clinical relevance of this is unknown. A dose reduction may be considered when combining lansoprazole with the CYP2C19 inhibitor fluvoxamine. A study shows that the plasma concentrations of lansoprazole increase up to 4-fold. Therefore lansoprazole should be taken at least 1 hour after taking these medicinal products.
This helps to prevent ulcers from forming, or assists the healing process where damage has already occurred. By decreasing the amount of acid, they can also help to reduce the symptoms of acid reflux disease, such as heartburn.
Lansoprazole is also given as one part of a treatment to get rid of Helicobacter pylori , a bacterium found in the stomach, which can cause ulcers. Before taking lansoprazole Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken.
For these reasons, before you start taking lansoprazole it is important that your doctor or pharmacist knows: If you are pregnant, trying for a baby or breast-feeding. If you have any problems with the way your liver works.
If you have any of the following symptoms: If you have ever had an allergic reaction to a medicine. If you are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines. How to take lansoprazole Before you start this treatment, read the manufacturer's printed information leaflet from inside the pack.
It will give you more information about lansoprazole and will provide you with a full list of the side-effects which you may experience from taking it. Take lansoprazole exactly as your doctor tells you to. There are different strengths of tablets and capsules available so your doctor will tell you which is right for you.
It is usually taken once a day in the morning. If you are taking it for either Helicobacter pylori eradication or for Zollinger-Ellison syndrome, it is likely you will be asked to take two doses a day. Your doctor will tell you which dose is right for you and the directions will also be on the label of the pack to remind you.
Any specific brand name of this medication 15mg not be available in all of the lansoprazole or approved for all of the conditions discussed here. Please report any suspected side effect on the Yellow Card Scheme website. Lansoprazole works by reducing the amount of acid that your stomach makes. For initial treatment of severe erosive esophagitis and gastric ulcerthe recommended dose for adults is 30 mg daily for weeks, lansoprazole gr 15mg. This 15mg to prevent ulcers from forming, or assists the healing process where damage has already occurred. The treatment for the prevention of peptic ulceration of patients in need of continuous NSAID treatment should be restricted to high risk patients e. Lansoprazole not take two doses at the same time to make up for a forgotten dose, lansoprazole gr 15mg. The information in this database is intended to supplement, not substitute for, the expertise and judgement of lansoprazole professionals, lansoprazole gr 15mg. If you experience any allergic reactions to the medicine, stop taking them immediately and contact your doctor. Lansoprazole side effects Get 15mg medical help if you have signs of an allergic reaction to lansoprazole: Is there an optimal degree of acid suppression for healing of duodenal ulcer?
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